The Migraine-Gluten Connection: What Science Says

Becky avatarPublished by | Last updated 23rd May, 2025

Emerging research suggests gluten is very likely a potential trigger for some migraine sufferers. Understanding this link may help individuals explore dietary changes alongside medical options.

Migraines aren’t merely debilitating headaches, but rather intricate neurological occurrences that can be initiated by multiple triggers. Diet for some is even more likely to influence their occurrence and severity.

One food component under close investigation is gluten, especially in individuals with coeliac disease or gluten sensitivity.

migraine links to celiac disease

How Migraines Are More Than Just Headaches

Migraines are severe, frequently incapacitating headaches that can be associated with nausea, sensitivity to light, visual disturbances and other neurological signs and symptoms. They occur in approximately 1 to 2.2% of people worldwide and can seriously impair your quality of life if you suffer from them.

Triggers are highly individualised and can include stress, sleep disturbances, hormonal changes, environmental stimuli and specific foods.

Identification of your triggers is also important in effective migraine control and diet is an area that is of rising interest. Chocolate, strong cheese and red wine are more classically known offenders, but gluten, a protein in wheat, barley and rye, is being increasingly studied as a potential contributing cause.

What is Gluten and Why Could it be an Issue?

Gluten is a naturally occurring protein within most grains that is responsible for making bread flexible and giving it structure, yet to some, ingesting gluten produces negative symptoms. In coeliac disease, gluten provokes an autoimmune attack that destroys the small intestine.

Others suffer from non-coeliac gluten sensitivity, where symptoms result from gluten, even though an autoimmune attack does not occur.

Scientific research suggests that in some individuals, most probably those with gluten disorders, gluten consumption is associated with neurological symptoms, such as migraines.

Certain studies propose that gluten might be responsible for provoking inflammatory pathways or activating immune processes that target the nervous system, perhaps to increase or worsen migraines.

Should You Attempt a Gluten-Free Diet?

If you think that gluten is causing your migraines, you should start by consulting your healthcare provider. Coeliac disease can be diagnosed using blood tests and confirmed by an intestinal biopsy.

Diagnoses of non-coeliac gluten sensitivity, on the other hand, are more problematic and typically based upon symptoms and the elimination of other causes.

It is also crucial to emphasise that if you are looking to pursue treatment, be it changes to diet or prescription medication, you should do so in an appropriate healthcare setting. In the United Kingdom, requests for prescription medication involve a consultation, whether in-person or online, with a registered professional to ensure safe and appropriate use.

For instance, people looking to use migraine medications such as Sumatriptan can utilise UK Meds online consultation for Sumatriptan, which provides an authoritative and compliant route to relief.

If you try an elimination diet that is gluten-free, it needs to be done consistently, for an appropriate time (usually 6–8 weeks) to ascertain effectiveness. A migraine diary to monitor frequency, severity and associated symptoms before and subsequently following the change of diet is also recommended.

If migraines get better, gluten could well be a contributory factor.

More on Gluten and the Risk of Migraines

Coeliac disease is known to afflict no fewer than 1 in every 100 people in both the UK and Europe, yet just 36% of individuals who suffer from it are actually clinically diagnosed.

This means that tens of thousands of individuals may be unwittingly ingesting gluten and suffering from associated health issues, such as migraines. An increasing number of studies indicate that individuals who suffer from coeliac disease experience migraines more than the average population. In individuals with non-coeliac gluten sensitivity, however, the association of gluten and migraines is more anecdotal but no less persuasive.

Numerous patients report reduced migraine occurrence following the institution of a gluten-free diet, although additional research is needed to establish cause and effect. If you are a migraine patient investigating food triggers, it is a good idea to speak to a health professional about gluten intolerance if other symptoms such as bloating, tiredness, or diarrhoea occur as well.

What the Experts Actually Say

The scientific consensus on gluten’s association with migraines continues to be evolving. Whereas studies confirm an association, especially among individuals with coeliac disease, the data remains uncertain for both coeliacs and the general population.

Clinicians do, however, consider it appropriate to trial a gluten-free diet if an individual experiences a pattern of gluten consumption and migraine development.

But experts warn not to self-diagnose or drastically change diets without expert advice. A gluten-free diet, while possibly beneficial to some, is limiting and may cause nutrient deficiencies if not carefully controlled.

Gluten: A Part of The Migraine Puzzle

Gluten is not likely to be a universal migraine cause, but it might be crucial for some, particularly those who suffer from coeliac disease or gluten sensitivity. Continuing research is casting more light on this relationship and future research studies might show who might gain most from therapeutic diets. In the interim, migraine treatment is still extremely individualised.

Whether you’re considering diet modification, taking prescription medications, or integrating both strategies, an evidence-guided plan can be life-changing. If you suffer from migraines, don’t be afraid to pursue every option—your well-being, comfort and quality of life are well worth it!

Key Takeaways

Gluten may trigger migraines in some people, especially those with gluten sensitivity

For some migraine sufferers, particularly people with coeliac disease or non-coeliac gluten sensitivity, gluten could be a trigger. Scientists believe that gluten may affect the nervous system in certain individuals, possibly causing or worsening migraine attacks.

A gluten-free diet might help, but only under medical supervision

If you think gluten could be linked to your migraines, speak to a healthcare professional before changing your diet. Trying a gluten-free diet for 6-8 weeks while keeping a migraine diary can help show if there’s a connection, but it’s important to do this safely and with proper advice to avoid missing out on key nutrients.

Migraine care should be personalised and evidence-based

Not everyone with migraines is affected by gluten, but exploring food triggers with the support of a doctor can be helpful. Treatments like Sumatriptan are available through services like UK Meds with an online consultation, allowing you to manage migraines with guidance tailored to your needs.

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Becky Terrell ✍️

Becky avatarHi, I am Becky. I am a passionate recipe maker and having been a coeliac (celiac) for 30+ years I focus on gluten-free recipes. My blog is my online cookbook of gluten-free tasty recipes. You can follow me on X: @beckygwg
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